Welcome

August 28, 2014

 
Welcome to LNCipedia 3.0, the latest version of this long non-coding RNA database contains 113,513 human annotated lncRNAs.

Introduction

Long non-coding RNA (lncRNA) constitutes a large and diverse class of non-coding RNA genes. While several lncRNAs have been functionally annotated, the majority remains to be characterized. Different high-throughput methods to identify new lncRNAs (including RNA sequencing and annotation of chromatin-state maps) have been applied in various studies resulting in multiple unrelated lncRNA datasets.

Lncipedia.org is an integrated database of 113,513 human annotated lncRNA transcripts obtained from different sources. In addition to basic transcript information and structure, several statistics are calculated for each entry in the database, such as secondary structure information, protein coding potential and microRNA binding sites.

The database is publicly available and allows users to query and download lncRNA sequences and structures based on different search criteria. The database may serve as a source of information on individual lncRNAs or as a starting point for large-scale studies.

Data submission

The lncRNA research community is encouraged to submit data to LNCipedia:



Citing

Please use the following citation when referring to LNCipedia:

LNCipedia: a database for annotated human lncRNA transcript sequences and structures
Pieter-Jan Volders; Kenny Helsens; Xiaowei Wang; Bjorn Menten; Lennart Martens; Kris Gevaert; Jo Vandesompele; Pieter Mestdagh
Nucleic Acids Research 2012; doi: 10.1093/nar/gks915

Citations: Google Scholar


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Recently added literature

2014-08-28: lnc-SMUG1-7
Qiu (2014)
Overexpression of long non-coding RNA HOTAIR predicts poor patient prognosis and promotes tumor metastasis in epithelial ovarian cancer.
(Gynecologic oncology)


2014-08-28: lnc-CLIC6-2
Morton (2014)
Identification of mRNAs and lincRNAs associated with lung cancer progression using next-generation RNA sequencing from laser micro-dissected archival FFPE tissue specimens.
(Lung cancer (Amsterdam, Netherlands))


2014-08-28: lnc-AGXT2L1-1
Shi (2014)
Low expression of novel lncRNA RP11-462C24.1 suggests a biomarker of poor prognosis in colorectal cancer.
(Medical oncology (Northwood, London, England))


2014-08-28: lnc-WBSCR22-1
Lin (2014)
Increased expression of long noncoding RNA ABHD11-AS1 in gastric cancer and its clinical significance.
(Medical oncology (Northwood, London, England))


2014-08-20: lnc-C11orf89-3
Zhu (2014)
lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI.
(The FEBS journal)


2014-08-20: lnc-MYC-2
Wang (2014)
Oncofetal Long Noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2.
(Hepatology (Baltimore, Md.))


2014-08-20: lnc-OR10H5-2
Wang (2014)
Hsa-miR-1 downregulates long non-coding RNA urothelial cancer associated 1 in bladder cancer.
(Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine)


2014-08-20: lnc-OR10H5-1
Wang (2014)
Hsa-miR-1 downregulates long non-coding RNA urothelial cancer associated 1 in bladder cancer.
(Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine)


2014-08-20: lnc-RP11-540D14.8.1-1
Gómez-Maldonado (2014)
EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination.
(Oncogene)


2014-08-19: lnc-SCYL1-1
Ji (2014)
Long non-coding RNA MALAT1 promotes tumour growth and metastasis in colorectal cancer through binding to SFPQ and releasing oncogene PTBP2 from SFPQ/PTBP2 complex.
(British journal of cancer)