Welcome

February 10, 2015

 
Welcome to LNCipedia 3.1, the latest version of this long non-coding RNA database contains 111,685 human annotated lncRNAs.

Introduction

Long non-coding RNA (lncRNA) constitutes a large and diverse class of non-coding RNA genes. While several lncRNAs have been functionally annotated, the majority remains to be characterized. Different high-throughput methods to identify new lncRNAs (including RNA sequencing and annotation of chromatin-state maps) have been applied in various studies resulting in multiple unrelated lncRNA datasets.

Lncipedia.org is an integrated database of 111,685 human annotated lncRNA transcripts obtained from different sources. In addition to basic transcript information and structure, several statistics are calculated for each entry in the database, such as secondary structure information, protein coding potential and microRNA binding sites.

The database is publicly available and allows users to query and download lncRNA sequences and structures based on different search criteria. The database may serve as a source of information on individual lncRNAs or as a starting point for large-scale studies.

Data submission

The lncRNA research community is encouraged to submit data to LNCipedia:



Citing

Please use the following citations when referring to LNCipedia:

An update on LNCipedia: a database for annotated human lncRNA sequences
Pieter-Jan Volders; Kenneth Verheggen; Gerben Menschaert; Klaas Vandepoele; Lennart Martens; Jo Vandesompele and Pieter Mestdagh
Nucleic Acids Research 2014; doi: 10.1093/nar/gku1060

LNCipedia: a database for annotated human lncRNA transcript sequences and structures
Pieter-Jan Volders; Kenny Helsens; Xiaowei Wang; Bjorn Menten; Lennart Martens; Kris Gevaert; Jo Vandesompele; Pieter Mestdagh
Nucleic Acids Research 2012; doi: 10.1093/nar/gks915

Citations: Google Scholar


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Recently added literature

2015-08-26: lnc-KCTD1-1
Crea (2014)
Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer.
(Oncotarget)


2015-08-26: lnc-SCYL1-1
Yan (2014)
Aberrant expression of long noncoding RNAs in early diabetic retinopathy.
(Investigative ophthalmology & visual science)


2015-08-26: lnc-FRG1-3
Soreq (2014)
Long non-coding RNA and alternative splicing modulations in Parkinson's leukocytes identified by RNA sequencing.
(PLoS computational biology)


2015-08-25: lnc-C11orf89-3
Keniry (2012)
The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r.
(Nature cell biology)


2015-07-31: lnc-OSBP2-2
Cai (2015)
The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144.
(Oncotarget)


2015-06-03: lnc-FOXB2-1
Ferreira (2013)
PCA3 noncoding RNA is involved in the control of prostate-cancer cell survival and modulates androgen receptor signaling.
(BMC cancer)


2015-05-25: lnc-AC012652.1.1-1
Wu (2015)
Association of large intergenic noncoding RNA expression with disease activity and organ damage in systemic lupus erythematosus.
(Arthritis research & therapy)


2015-05-25: lnc-AC012652.1.1-2
Wu (2015)
Association of large intergenic noncoding RNA expression with disease activity and organ damage in systemic lupus erythematosus.
(Arthritis research & therapy)


2015-05-25: lnc-LPO-1
Wu (2015)
Association of large intergenic noncoding RNA expression with disease activity and organ damage in systemic lupus erythematosus.
(Arthritis research & therapy)


2015-05-25: lnc-DHX37-1
Wu (2015)
Association of large intergenic noncoding RNA expression with disease activity and organ damage in systemic lupus erythematosus.
(Arthritis research & therapy)