Welcome

May 25, 2016

 
Welcome to LNCipedia 4.0, the latest version of this long non-coding RNA database contains 118,777 human annotated lncRNAs.

Introduction

Long non-coding RNA (lncRNA) constitutes a large and diverse class of non-coding RNA genes. While several lncRNAs have been functionally annotated, the majority remains to be characterized. Different high-throughput methods to identify new lncRNAs (including RNA sequencing and annotation of chromatin-state maps) have been applied in various studies resulting in multiple unrelated lncRNA datasets.

Lncipedia.org is an integrated database of 118,777 human annotated lncRNA transcripts obtained from different sources. In addition to basic transcript information and structure, several statistics are calculated for each entry in the database, such as secondary structure information, protein coding potential and microRNA binding sites.

The database is publicly available and allows users to query and download lncRNA sequences and structures based on different search criteria. The database may serve as a source of information on individual lncRNAs or as a starting point for large-scale studies.

Data submission

The lncRNA research community is encouraged to submit data to LNCipedia:



Citing

Please use the following citations when referring to LNCipedia:

An update on LNCipedia: a database for annotated human lncRNA sequences
Pieter-Jan Volders; Kenneth Verheggen; Gerben Menschaert; Klaas Vandepoele; Lennart Martens; Jo Vandesompele and Pieter Mestdagh
Nucleic Acids Research 2014; doi: 10.1093/nar/gku1060
 [citations in Google Scholar]

LNCipedia: a database for annotated human lncRNA transcript sequences and structures
Pieter-Jan Volders; Kenny Helsens; Xiaowei Wang; Bjorn Menten; Lennart Martens; Kris Gevaert; Jo Vandesompele; Pieter Mestdagh
Nucleic Acids Research 2012; doi: 10.1093/nar/gks915
 [citations in Google Scholar]


Twitter

Recently added literature

2016-05-25: SAMMSON
Leucci (2016)
Melanoma addiction to the long non-coding RNA SAMMSON.
(Nature)


2016-05-10: PVT1
Johnsson (2014)
Expanding the functional role of long noncoding RNAs.
(Cell research)


2016-05-10: PVT1
Paci (2014)
Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer.
(BMC systems biology)


2016-05-10: PVT1
Wang (2014)
Oncofetal Long Noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2.
(Hepatology (Baltimore, Md.))


2016-05-10: PVT1
Shih (2015)
Non-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism.
(International journal of molecular sciences)


2016-05-10: PVT1
Li (2016)
Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cells.
(Nucleic acids research)


2016-05-10: PVT1
Ragusa (2015)
Non-coding landscapes of colorectal cancer.
(World journal of gastroenterology)


2016-05-10: PVT1
Guo (2015)
Competing endogenous RNA networks and gastric cancer.
(World journal of gastroenterology)


2016-05-10: PVT1
Pei (2015)
Notch-1 promotes breast cancer cells proliferation by regulating LncRNA GAS5.
(International journal of clinical and experimental medicine)


2016-05-10: PVT1
Na (2015)
Long non-coding RNA UCA1 contributes to the progression of prostate cancer and regulates proliferation through KLF4-KRT6/13 signaling pathway.
(International journal of clinical and experimental medicine)